Gene information
Official symbol P2RY12
Official full name purinergic receptor P2Y12
Gene type protein-coding gene
Chromosome3q25.1
Alias symbolP2Y12; SP1999; HORK3
Gene familyP2Y receptors
Resources
Entrez Gene 64805
HGNC HGNC:18124
Ensembl ENSG00000169313
Vega OTTHUMG00000159863
UCSC uc003eyx.3
GO terms: 44 records
GO Description Category LogP Number of genes Detail
GO:0001667 ameboidal-type cell migration GO Biological Processes -17.0771232 40 More
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007420 brain development GO Biological Processes -11.5572036 75 More
GO:0019216 regulation of lipid metabolic process GO Biological Processes -24.8423986 38 More
GO:0019722 calcium-mediated signaling GO Biological Processes -11.6647584 29 More
GO:0019932 second-messenger-mediated signaling GO Biological Processes -19.1717114 46 More
GO:0021537 telencephalon development GO Biological Processes -6.21909725 29 More
GO:0021543 pallium development GO Biological Processes -4.55337429 20 More
GO:0021987 cerebral cortex development GO Biological Processes -4.14759222 15 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030900 forebrain development GO Biological Processes -11.1545964 48 More
GO:0031253 cell projection membrane GO Cellular Components -3.08510132 12 More
GO:0031334 positive regulation of protein-containing complex assembly GO Biological Processes -8.84926570 16 More
GO:0031344 regulation of cell projection organization GO Biological Processes -8.91314416 62 More
GO:0031346 positive regulation of cell projection organization GO Biological Processes -6.78114948 37 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042063 gliogenesis GO Biological Processes -20.3412228 47 More
GO:0043254 regulation of protein-containing complex assembly GO Biological Processes -7.63830100 21 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043270 positive regulation of ion transport GO Biological Processes -23.5832054 34 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0044089 positive regulation of cellular component biogenesis GO Biological Processes -10.7794496 56 More
GO:0044297 cell body GO Cellular Components -11.7206640 62 More
GO:0045834 positive regulation of lipid metabolic process GO Biological Processes -24.1838255 28 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051897 positive regulation of protein kinase B signaling GO Biological Processes -23.7578366 39 More
GO:0060191 regulation of lipase activity GO Biological Processes -10.2745708 13 More
GO:0060193 positive regulation of lipase activity GO Biological Processes -9.32996784 11 More
GO:0060322 head development GO Biological Processes -11.995356 79 More
GO:0060491 regulation of cell projection assembly GO Biological Processes -2.36338574 17 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0098609 cell-cell adhesion GO Biological Processes -15.7963965 69 More
GO:0120032 regulation of plasma membrane bounded cell projection assembly GO Biological Processes -2.40785708 17 More
GO:0120035 regulation of plasma membrane bounded cell projection organization GO Biological Processes -8.54789693 60 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1903975 regulation of glial cell migration GO Biological Processes -5.72938190 7 More
GO:1903977 positive regulation of glial cell migration GO Biological Processes -7.18867136 7 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
Drug-Gene interaction
view
Related drugs: 14 records
Drug name Interaction type Source PMID View
brilinta TTD view
cangrelor antagonistinhibitor TdgClinicalTrialPharmGKBTTD 2640273520126830 view
cangrelor tetrasodium antagonist ChemblInteractions view
clopidogrel antagonist TdgClinicalTrialTENDTTD 152698271946337516835302151994741529196914668029126156911175235215308557 view
clopidogrel bisulfate antagonist ChemblInteractions view
cytarabine PharmGKB 24444404 view
elinogrel antagonist TdgClinicalTrialChemblInteractionsTTD view
prasugrel antagonist TdgClinicalTrialTENDPharmGKBTTD 209383711848508624951432 view
prasugrel hydrochloride antagonist ChemblInteractions view
regrelor disodium antagonist TdgClinicalTrialChemblInteractionsTTD view
ticagrelor inhibitorantagonist TdgClinicalTrialChemblInteractionsPharmGKB 26063049178270082495143217980251 view
ticlopidine antagonist TdgClinicalTrialTENDPharmGKB 158165041145425420938371171101461595556511752352 view
ticlopidine hydrochloride antagonist ChemblInteractions view
treprostinil agonist TdgClinicalTrialTEND 304857281713928417016423 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_022788.5:c.36T>G genomics ischemic cardiac events[prognosis (bad)] ST elevation myocardial infarction Zhang JH et al. Platelets. 2016
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